Modulating the analytical performance of an electrochemical biosensor through varying, at the working electrode, the surface area ratio between that covered by the enzyme and the enzyme-free one

Abstract

It is shown that the analytical features namely the sensitivity, the lowest detection (LOD) and quantification (LOQ) limits and the apparent Michaelis–Menten's (K′_m) constant as well, of a Laccasa-based electrochemical biosensor for hydroquinone (HQ) quantification, depend on the transductor's area ratio, between that covered with the enzyme and the enzyme-free one.