Issue 2, 2015
From the journal:

Chemical Communications

Refractive index dependent real-time plasmonic nanoprobes on a single silver nanocube for ultrasensitive detection of the lung cancer-associated miRNAs†

Lei Zhang,‡a   Ying Zhang,‡a   Yanling Hu,a   Quli Fan,a   Wenjing Yang,a   Anran Li,b   Shuzhou Li,*b   Wei Huang*ac  and  Lianhui Wang*a  

* Corresponding authors

a Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China
E-mail: iamlhwang@njupt.edu.cn

b Division of Materials Science, School of Materials Science and Engineering, Nanyang Avenue, Singapore
E-mail: lisz@ntu.edu.sg

c Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, China
E-mail: iamwhuang@njupt.edu.cn

Abstract

We developed a novel method for the real-time monitoring of the delicate change in refractive index (RI) when DNA or RNA hybridize near a DNA-capped silver nanocube (AgNC) surface. This method offers an alternative platform in the quantitative analysis of the trace lung cancer-associated miRNAs in label-free detection.

Graphical abstract: Refractive index dependent real-time plasmonic nanoprobes on a single silver nanocube for ultrasensitive detection of the lung cancer-associated miRNAs

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Article information

DOI
https://doi.org/10.1039/C4CC06663D
Article type
Communication
Submitted
24 Aug 2014
Accepted
16 Oct 2014
First published
16 Oct 2014

Chem. Commun., 2015,51, 294-297

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Refractive index dependent real-time plasmonic nanoprobes on a single silver nanocube for ultrasensitive detection of the lung cancer-associated miRNAs

L. Zhang, Y. Zhang, Y. Hu, Q. Fan, W. Yang, A. Li, S. Li, W. Huang and L. Wang, Chem. Commun., 2015, 51, 294 DOI: 10.1039/C4CC06663D

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