Issue 4, 2015
From the journal:

Chemical Communications

Label-free detection of Alzheimer’s disease through the ADP3 peptoid recognizing the serum amyloid-beta42 peptide†

Zijian Zhao,‡a   Ling Zhu,‡*a   Xiangli Bu,a   Huailei Ma,a   Shu Yang,a   Yanlian Yanga  and  Zhiyuan Hu*a  

* Corresponding authors

a National Center for Nanoscience and Technology, No. 11, Beiyitiao Zhongguancun, Beijing, P.R. China
E-mail: zhul@nanoctr.cn, huzy@nanoctr.cn

Abstract

The early diagnosis of Alzheimer’s disease (AD) is challenging due to the lack of reliable methods for detecting its biomarkers in the noninvasive biopsies. We used surface plasmon resonance imaging to identify AD based on the detection of amyloid-beta42 in the serum by the ADP3 peptoid.

Graphical abstract: Label-free detection of Alzheimer’s disease through the ADP3 peptoid recognizing the serum amyloid-beta42 peptide

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Article information

DOI
https://doi.org/10.1039/C4CC07037B
Article type
Communication
Submitted
06 Sep 2014
Accepted
18 Nov 2014
First published
18 Nov 2014

Chem. Commun., 2015,51, 718-721

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Label-free detection of Alzheimer’s disease through the ADP3 peptoid recognizing the serum amyloid-beta42 peptide

Z. Zhao, L. Zhu, X. Bu, H. Ma, S. Yang, Y. Yang and Z. Hu, Chem. Commun., 2015, 51, 718 DOI: 10.1039/C4CC07037B

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