Issue 8, 2015
From the journal:

Chemical Communications

A multi-functional probe to discriminate Lys, Arg, His, Cys, Hcy and GSH from common amino acids†

Xiuhong Lu,a   Wen Wang,a   Qian Dong,a   Xiaolong Bao,a   Xianfeng Lin,a   Weixing Zhang,a   Xiaochun Dong*a  and  Weili Zhao*ab  

* Corresponding authors

a School of Pharmacy, Fudan University, Shanghai, P. R. China
E-mail: xcdong@fudan.edu.cn, zhaoweili@fudan.edu.cn
Fax: +86-21-51980111
Tel: +86-21-51980111

b Key Laboratory for Special Functional Materials of the Ministry of Education, Henan University, Kaifeng, P. R. China
E-mail: zhaow@henu.edu.cn
Fax: +86-371-23881358
Tel: +86-371-23881358

Abstract

The co-existence and similar properties of amino acids make the detection of individual amino acids challenging. Herein we discovered that probe 1 may act as a smart example to classify and differentiate basic amino acids (Arg/Lys/His), thiol-containing amino acids (Cys/HCy), and GSH through different sensing mechanisms in selected environments.

Graphical abstract: A multi-functional probe to discriminate Lys, Arg, His, Cys, Hcy and GSH from common amino acids

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Article information

DOI
https://doi.org/10.1039/C4CC07757A
Article type
Communication
Submitted
05 Oct 2014
Accepted
03 Dec 2014
First published
03 Dec 2014

Chem. Commun., 2015,51, 1498-1501

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A multi-functional probe to discriminate Lys, Arg, His, Cys, Hcy and GSH from common amino acids

X. Lu, W. Wang, Q. Dong, X. Bao, X. Lin, W. Zhang, X. Dong and W. Zhao, Chem. Commun., 2015, 51, 1498 DOI: 10.1039/C4CC07757A

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