A three-step synthesis of benzo[c]thiophenes is presented in which the key transformation is the gold-catalyzed 5-exo-dig migratory cycloisomerization of a diallyl thioacetal. It was shown that a small amount of in situ generated HAuCl4 from AuCl3 is the active catalytic species. A mechanism was proposed.
![Graphical abstract: Gold superacid-catalyzed preparation of benzo[c]thiophenes](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C4CC07989B&imageInfo.ImageIdentifier.Year=2015)
W. Debrouwer, R. A. J. Seigneur, T. S. A. Heugebaert and C. V. Stevens, Chem. Commun., 2015, 51, 729 DOI: 10.1039/C4CC07989B
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