Issue 11, 2015
From the journal:

Chemical Communications

A highly selective and sensitive fluorescent thiol probe through dual-reactive and dual-quenching groups†

Huatang Zhang,‡a   Changyu Zhang,‡b   Ruochuan Liu,a   Long Yi*bc  and  Hongyan Sun*a  

* Corresponding authors

a Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, P. R. China
E-mail: hongysun@cityu.edu.hk
Fax: +852 34420522
Tel: +852 34429537

b State Key Laboratory of Organic-Inorganic Composites and Beijing University of Chemical Technology, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Chaoyang District, Beijing 100029, China
E-mail: yilong@mail.buct.edu.cn

c Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, China

Abstract

A new fluorescent probe installed with dual-reactive and dual-quenching groups was rationally designed for highly selective and sensitive sensing of biothiols. The sensitivity of the probe toward thiols was significantly improved by dual-quenching effects. Furthermore the selectivity of the probe was also greatly enhanced by installation of dual-reactive groups.

Graphical abstract: A highly selective and sensitive fluorescent thiol probe through dual-reactive and dual-quenching groups

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Article information

DOI
https://doi.org/10.1039/C4CC08156K
Article type
Communication
Submitted
15 Oct 2014
Accepted
19 Nov 2014
First published
21 Nov 2014

Chem. Commun., 2015,51, 2029-2032

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A highly selective and sensitive fluorescent thiol probe through dual-reactive and dual-quenching groups

H. Zhang, C. Zhang, R. Liu, L. Yi and H. Sun, Chem. Commun., 2015, 51, 2029 DOI: 10.1039/C4CC08156K

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