Issue 4, 2015
From the journal:

Chemical Communications

Saccharides and temperature dual-responsive hydrogel layers for harvesting cell sheets†

Bingbing Guo,ab   Guoqing Pan,*ab   Qianping Guo,ab   Caihong Zhu,ab   Wenguo Cui,ab   Bin Li*ab  and  Huilin Yangab  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Orthopedic Institute, Soochow University, 708 Renmin Road, Suzhou, Jiangsu 215007, China
E-mail: yueer@suda.edu.cn, binli@suda.edu.cn

b Department of Orthopaedics, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, Jiangsu 215006, China

Abstract

Saccharides and temperature dual-responsive hydrogels have been prepared based on PNIPAAm copolymers containing phenylboronic acid (PBA) groups and used for harvesting cell sheets. The cell sheet could be released from the hydrogel layer at 37 °C simply by increasing sugar concentration, and could be more efficiently released at a lower temperature and elevated sugar concentration.

Graphical abstract: Saccharides and temperature dual-responsive hydrogel layers for harvesting cell sheets

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Article information

DOI
https://doi.org/10.1039/C4CC08183H
Article type
Communication
Submitted
15 Oct 2014
Accepted
13 Nov 2014
First published
13 Nov 2014

Chem. Commun., 2015,51, 644-647

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Saccharides and temperature dual-responsive hydrogel layers for harvesting cell sheets

B. Guo, G. Pan, Q. Guo, C. Zhu, W. Cui, B. Li and H. Yang, Chem. Commun., 2015, 51, 644 DOI: 10.1039/C4CC08183H

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