Issue 9, 2015
From the journal:

Chemical Communications

Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid†

Lei Wang,a   Martha Sibrian-Vazquez,a   Jorge O. Escobedo,a   Jialu Wang,a   Richard G. Mooreb  and  Robert M. Strongin*a  

* Corresponding authors

a Department of Chemistry, Portland State University, Portland, OR 97201, USA
E-mail: strongin@pdx.edu
Tel: +1-503-725-9724

b Women and Infants Hospital, Brown University, 101 Dudley Street, Providence, RI 02905, USA
E-mail: RMoore@wihri.org
Tel: +1-401-453-7520

Abstract

Direct determination of total lysophosphatidic acid (LPA) was accomplished using newly developed spiroguanidines derived from rhodamine B as universal fluorogenic probes. Optimum conditions for the quantitative analysis of total LPA were investigated. The linear range for the determination of total LPA is up to 5 μM with a limit of detection of 0.512 μM.

Graphical abstract: Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid

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Article information

DOI
https://doi.org/10.1039/C4CC08818B
Article type
Communication
Submitted
05 Nov 2014
Accepted
08 Dec 2014
First published
09 Dec 2014

Chem. Commun., 2015,51, 1697-1700

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Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid

L. Wang, M. Sibrian-Vazquez, J. O. Escobedo, J. Wang, R. G. Moore and R. M. Strongin, Chem. Commun., 2015, 51, 1697 DOI: 10.1039/C4CC08818B

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