Issue 20, 2015
From the journal:

Chemical Communications

A novel hydrophilic polymer-brush pattern for site-specific capture of blood cells from whole blood†

Jianwen Hou,ab   Qiang Shi,*a   Wei Ye,ab   Qunfu Fan,c   Hengchong Shi,a   Shing-Chung Wong,d   Xiaodong Xuc  and  Jinghua Yin*a  

* Corresponding authors

a State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China
E-mail: shiqiang@ciac.ac.cn, yinjh@ciac.ac.cn

b University of Chinese Academy of Sciences, Beijing 100049, P. R. China

c Polymer Materials Research Center, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, P. R. China

d Department of Mechanical Engineering, University of Akron, Akron, Ohio 44325-3903, USA

Abstract

A novel hydrophilic PAMPS–PAAm brush pattern is fabricated to selectively capture blood cells from whole blood. PAMPS brushes provide antifouling surfaces to resist protein and cell adhesion while PAAm brushes effectively entrap targeted proteins for site-specific and cell-type dependent capture of blood cells.

Graphical abstract: A novel hydrophilic polymer-brush pattern for site-specific capture of blood cells from whole blood

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Article information

DOI
https://doi.org/10.1039/C4CC09096A
Article type
Communication
Submitted
14 Nov 2014
Accepted
27 Nov 2014
First published
27 Nov 2014

Chem. Commun., 2015,51, 4200-4203

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A novel hydrophilic polymer-brush pattern for site-specific capture of blood cells from whole blood

J. Hou, Q. Shi, W. Ye, Q. Fan, H. Shi, S. Wong, X. Xu and J. Yin, Chem. Commun., 2015, 51, 4200 DOI: 10.1039/C4CC09096A

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