The glutathione-coordinated [2Fe–2S] cluster is demonstrated to be a viable and likely substrate for physiological iron–sulfur cluster transport by Atm1p, a mitochondrial ABC export protein. Flow cytometry and colorimetric assays demonstrate a quantitative methodology for study of metal translocation proteins and their proteoliposome products.
![Graphical abstract: Glutathione-coordinated [2Fe–2S] cluster: a viable physiological substrate for mitochondrial ABCB7 transport](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C4CC09175B&imageInfo.ImageIdentifier.Year=2015)
J. Li and J. A. Cowan, Chem. Commun., 2015, 51, 2253 DOI: 10.1039/C4CC09175B
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