Issue 21, 2015
From the journal:

Chemical Communications

Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids†

Fredrik Lindahl,*a   Huy N. Hoang,a   David P. Fairliea  and  Matthew A. Cooper*a  

* Corresponding authors

a Institute for Molecular Biosciences, University of Queensland, St. Lucia, QLD, Australia
E-mail: f.lindahl@imb.uq.edu.au, m.cooper@uq.edu.au

Abstract

A new methodology for the synthesis of side chain mono- or bis-methylated Fmoc-Dap, -Dab and -Orn amino acids was developed by probing the reactivity of commercially available Fmoc amino acids.

Graphical abstract: Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids

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Article information

DOI
https://doi.org/10.1039/C4CC09780G
Article type
Communication
Submitted
07 Dec 2014
Accepted
08 Feb 2015
First published
09 Feb 2015

Chem. Commun., 2015,51, 4496-4498

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Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids

F. Lindahl, H. N. Hoang, D. P. Fairlie and M. A. Cooper, Chem. Commun., 2015, 51, 4496 DOI: 10.1039/C4CC09780G

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