Real-time analysis of multiple anion mixtures in aqueous media using a single receptor

Abstract

Bambusuril-based receptors have been used in conjunction with ¹H NMR spectroscopy to recognize mixtures of inorganic anions in aqueous solutions. This was achieved by examining complexation-induced changes in the receptors’ ¹H NMR fingerprints. This approach enables the simultaneous identification of up to 9 anions and the quantification of up to 5 anions using a single receptor in DMSO-d₆ containing 5% D₂O. Toxic perchlorate was recognized and quantified at 0.1 μM (1.8 ppb, mol mol⁻¹) concentration in pure water.