Issue 23, 2015
From the journal:

Chemical Communications

Hydrazide macrocycles as effective transmembrane channels for ammonium†

Pengyang Xin,a   Liang Zhang,a   Pei Su,a   Jun-Li Hou*a  and  Zhan-Ting Li*a  

* Corresponding authors

a Department of Chemistry, Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), Fudan University, 220 Handan Road, Shanghai 200433, China
E-mail: houjl@fudan.edu.cn, ztli@fudan.edu.cn

Abstract

Three shape-persistent aromatic hydrazide macrocycles that bear phenylalanine tripeptide chains have been synthesized. These macrocycles can insert into lipid bilayers to form single-molecular ion channels which exhibit a high NH4+/K+ selectivity.

Graphical abstract: Hydrazide macrocycles as effective transmembrane channels for ammonium

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Article information

DOI
https://doi.org/10.1039/C5CC00691K
Article type
Communication
Submitted
24 Jan 2015
Accepted
10 Feb 2015
First published
11 Feb 2015

Chem. Commun., 2015,51, 4819-4822

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Hydrazide macrocycles as effective transmembrane channels for ammonium

P. Xin, L. Zhang, P. Su, J. Hou and Z. Li, Chem. Commun., 2015, 51, 4819 DOI: 10.1039/C5CC00691K

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