Issue 28, 2015

Stereoselective synthesis of a highly oxygenated decahydrocyclopenta[g]chromene derivative: the common tricyclic framework of leucosceptrine and leucosesterterpenone

Abstract

Stereoselective construction of the highly oxygenated decahydrocyclopenta[g]chromene skeleton, which is the tricyclic core of leucosceptrine, which possesses prolylendopeptidase inhibitory activity, and leucosesterterpenone, which exhibits anti-angiogenic activity, from Leucosceptrum canum, was achieved.

Graphical abstract: Stereoselective synthesis of a highly oxygenated decahydrocyclopenta[g]chromene derivative: the common tricyclic framework of leucosceptrine and leucosesterterpenone

Supplementary files

Article information

Article type
Communication
Submitted
30 Jan 2015
Accepted
25 Feb 2015
First published
27 Feb 2015

Chem. Commun., 2015,51, 6108-6110

Author version available

Stereoselective synthesis of a highly oxygenated decahydrocyclopenta[g]chromene derivative: the common tricyclic framework of leucosceptrine and leucosesterterpenone

H. Abe, Y. Horii, M. Hagiwara, T. Kobayashi and H. Ito, Chem. Commun., 2015, 51, 6108 DOI: 10.1039/C5CC00879D

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