Issue 29, 2015

Aggregates of silicon quantum dots as a drug carrier: selective intracellular drug release based on pH-responsive aggregation/dispersion

Abstract

Using amine-modified silicon quantum dots (Si-QDs) with visible photoluminescence as a building block, drug-loaded Si-QD aggregates were assembled. The aggregates were designed to break down in response to the endosomal pH decrease, which enabled the selective intracellular release of the loaded drugs.

Graphical abstract: Aggregates of silicon quantum dots as a drug carrier: selective intracellular drug release based on pH-responsive aggregation/dispersion

Supplementary files

Article information

Article type
Communication
Submitted
31 Jan 2015
Accepted
04 Mar 2015
First published
06 Mar 2015

Chem. Commun., 2015,51, 6422-6425

Author version available

Aggregates of silicon quantum dots as a drug carrier: selective intracellular drug release based on pH-responsive aggregation/dispersion

S. Ohta, K. Yamura, S. Inasawa and Y. Yamaguchi, Chem. Commun., 2015, 51, 6422 DOI: 10.1039/C5CC00925A

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