Pushing the limits of signal resolution to make coupling measurement easier

Abstract

Probing scalar couplings are essential for structural elucidation in molecular (bio)chemistry. While the measurement of J_HH couplings is facilitated by SERF experiments, overcrowded signals represent a significant limitation. Here, a new band selective pure shift SERF allows access to δ¹H and J_HH with an ultrahigh spectral resolution.