The first nickel-catalyzed method for the borylation of carbon–hydrogen bonds in arenes and indoles is described. The use of an N-heterocyclic carbene ligand is essential for an efficient reaction, with an N-cyclohexyl-substituted derivative being optimal. This method is readily applied to the gram scale synthesis of 2-borylindole.
T. Furukawa, M. Tobisu and N. Chatani, Chem. Commun., 2015, 51, 6508 DOI: 10.1039/C5CC01378J
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