Issue 41, 2015
From the journal:

Chemical Communications

Separation of liquid domains in model membranes induced with high hydrostatic pressure†

Nicola L. C. McCarthy,a   Oscar Ces,a   Robert V. Law,a   John M. Seddona  and  Nicholas J. Brooks*a  

* Corresponding authors

a Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, UK
E-mail: nicholas.brooks@imperial.ac.uk

Abstract

We have imaged the formation of membrane microdomains immediately after their induction using a novel technology platform coupling high hydrostatic pressure to fluorescence microscopy. After formation, the ordered domains are small and highly dynamic. This will enhance links between model lipid assemblies and dynamic processes in cellular membranes.

Graphical abstract: Separation of liquid domains in model membranes induced with high hydrostatic pressure

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Article information

DOI
https://doi.org/10.1039/C5CC02134K
Article type
Communication
Submitted
12 Mar 2015
Accepted
20 Apr 2015
First published
20 Apr 2015
This article is Open Access
Creative Commons BY license

Chem. Commun., 2015,51, 8675-8678

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Separation of liquid domains in model membranes induced with high hydrostatic pressure

N. L. C. McCarthy, O. Ces, R. V. Law, J. M. Seddon and N. J. Brooks, Chem. Commun., 2015, 51, 8675 DOI: 10.1039/C5CC02134K

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