Issue 64, 2015
From the journal:

Chemical Communications

Copper-catalyzed oxidative C–H/C–H cross-coupling of benzamides and thiophenes†

Sheng Zhao,a   Jun Yuan,a   Yi-Chen Lia  and  Bing-Feng Shi*a  

* Corresponding authors

a Department of Chemistry, Zhejiang University, 38 Zheda Rd., Hangzhou 310027, China
E-mail: bfshi@zju.edu.cn

Abstract

A copper-catalyzed oxidative C–H/C–H cross-coupling of benzamides and thiophenes has been developed. This reaction exhibits a broad substrate scope and excellent tolerance of functional groups. The directing group could be readily removed to afford 2-thienylbenzoic acids.

Graphical abstract: Copper-catalyzed oxidative C–H/C–H cross-coupling of benzamides and thiophenes

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Article information

DOI
https://doi.org/10.1039/C5CC05058H
Article type
Communication
Submitted
19 Jun 2015
Accepted
04 Jul 2015
First published
06 Jul 2015

Chem. Commun., 2015,51, 12823-12826

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Copper-catalyzed oxidative C–H/C–H cross-coupling of benzamides and thiophenes

S. Zhao, J. Yuan, Y. Li and B. Shi, Chem. Commun., 2015, 51, 12823 DOI: 10.1039/C5CC05058H

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