Issue 80, 2015
From the journal:

Chemical Communications

A thiol–thiosulfonate reaction providing a novel strategy for turn-on thiol sensing†

Chunpo Ge,a   Hao Wang,a   Baoxin Zhang,a   Juan Yao,a   Xinming Li,a   Weimin Feng,a   Panpan Zhou,a   Yawen Wanga  and  Jianguo Fang*a  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China
E-mail: fangjg@lzu.edu.cn

Abstract

The first thiol-specific turn-on probe, BODIPY-TS, utilizing a thiosulfonate scaffold as the thiol recognition unit was reported. BODIPY-TS displays low toxicity, and features high sensitivity, fast response and quantitative reaction towards thiols. The structural novelty of BODIPY-TS would guide the development of novel thiol probes.

Graphical abstract: A thiol–thiosulfonate reaction providing a novel strategy for turn-on thiol sensing

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Article information

DOI
https://doi.org/10.1039/C5CC05390K
Article type
Communication
Submitted
30 Jun 2015
Accepted
18 Aug 2015
First published
18 Aug 2015

Chem. Commun., 2015,51, 14913-14916

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A thiol–thiosulfonate reaction providing a novel strategy for turn-on thiol sensing

C. Ge, H. Wang, B. Zhang, J. Yao, X. Li, W. Feng, P. Zhou, Y. Wang and J. Fang, Chem. Commun., 2015, 51, 14913 DOI: 10.1039/C5CC05390K

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