Issue 26, 2015

Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles

Abstract

In the present work, we study different physicochemical properties of the spontaneous unilamellar vesicles created by the catanionic ionic liquid-like surfactant benzyl-n-hexadecyldimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-BHD), using two different fluorescent probes: 6-propionyl-2-(dimethylaminonaphthalene), PRODAN and trans-4-[4-(dimethylamino)-styryl]-1-methylpyridinium iodide, HC. Steady-state and time resolved fluorescence emission spectroscopy allowed us to find the unique properties of the AOT-BHD bilayer in comparison with vesicles formed using the traditional phospholipid 1,2-di-oleoyl-sn-glycero-3-phosphatidylcholine, DOPC. From the emission results, we observed that the region of the bilayer close to the polar head of AOT-BHD is a powerful electron donor environment, even larger than DOPC. Additionally, the AOT-BHD bilayer offers a less polar and slightly more viscous zone than DOPC. Thus, this particular bilayer is able to produce large incorporation of ionic and nonionic molecules and is very promising to be used as a nanocarrier in pharmacological, cosmetic and food fields.

Graphical abstract: Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles

Supplementary files

Article information

Article type
Paper
Submitted
24 Apr 2015
Accepted
04 Jun 2015
First published
04 Jun 2015

Phys. Chem. Chem. Phys., 2015,17, 17112-17121

Author version available

Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles

C. C. Villa, N. M. Correa, J. J. Silber, F. Moyano and R. D. Falcone, Phys. Chem. Chem. Phys., 2015, 17, 17112 DOI: 10.1039/C5CP02387D

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