Issue 12, 2015

Copper(i)-catalyzed amidation reaction of organoboronic esters and isocyanates

Abstract

A simple and efficient methodology for the preparation of amides from easily available organoboronic esters and isocyanates has been accomplished using a ligand-free copper(I) catalyst. The reaction system demonstrated a broad substrate scope and provided convenient access to a wide variety of secondary amides.

Graphical abstract: Copper(i)-catalyzed amidation reaction of organoboronic esters and isocyanates

Supplementary files

Article information

Article type
Communication
Submitted
19 Jun 2015
Accepted
31 Jul 2015
First published
31 Jul 2015

Green Chem., 2015,17, 5140-5143

Copper(I)-catalyzed amidation reaction of organoboronic esters and isocyanates

T. T. S. Lew, D. S. W. Lim and Y. Zhang, Green Chem., 2015, 17, 5140 DOI: 10.1039/C5GC01374G

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