A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.
G. Cheng, S. Hao, X. Yu and S. Zheng, Lab Chip, 2015, 15, 650 DOI: 10.1039/C4LC01165A
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