The current graphene safety landscape – a literature mining exercise

Abstract

As for any novel nanomaterial, the development of applications and industrial adoption of graphene-based materials will be subject to the confirmation of their safety profile and risk assessment. The analysis performed here maps the current knowledge of the safety of graphene-based materials as extracted by a literature mapping exercise of studies investigating these materials in preclinical animal models. We attempt to identify gaps for future studies and elucidate the critically important structure–function correlations between reported biological effects and graphene-based material physicochemical characteristics.