Issue 1, 2015

Functional importance of the sugar moiety of jasmonic acid glucoside for bioactivity and target affinity

Abstract

12-O-β-D-Glucopyranosyljasmonic acid (JAG, 1) induces nyctinastic leaf-folding of Samanea saman. The SAR studies of 1 revealed the unique role of its glycone moiety. Biological activity and the target affinity of 1 were affected by the stereochemistry of the glycone moiety. JAG belongs to a unique class of ligands in which the structure of the glycone moiety is involved in the molecular recognition by the target protein.

Graphical abstract: Functional importance of the sugar moiety of jasmonic acid glucoside for bioactivity and target affinity

Supplementary files

Article information

Article type
Communication
Submitted
02 Oct 2014
Accepted
15 Oct 2014
First published
15 Oct 2014

Org. Biomol. Chem., 2015,13, 55-58

Author version available

Functional importance of the sugar moiety of jasmonic acid glucoside for bioactivity and target affinity

M. Ueda, G. Yang, Y. Nukadzuka, Y. Ishimaru, S. Tamura and Y. Manabe, Org. Biomol. Chem., 2015, 13, 55 DOI: 10.1039/C4OB02106A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements