Various tetrasubstituted pyrroles/pyrazoles have been prepared from nitro-substituted 1,3-enynes with aromatic amines/hydrazines via a copper-catalyzed cascade aza-Michael addition, cyclization and aromatization at room temperature. This protocol is also effective for the synthesis of tetrasubstituted pyrazoles in high yields.
G. Bharathiraja, M. Sengoden, M. Kannan and T. Punniyamurthy, Org. Biomol. Chem., 2015, 13, 2786 DOI: 10.1039/C4OB02508C
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