A copper-mediated tandem reaction of β-ketoesters/ketones with tertiary amines was achieved, which provides a simple and efficient approach to the synthesis of 2,3-dihydrofuran derivatives. In this tandem reaction, the tertiary amine not only offers the methylene moiety but also serves as the base.
S. Guo, L. Lu, J. Gong, Z. Zhu, F. Xu, Z. Wei and H. Cai, Org. Biomol. Chem., 2015, 13, 4426 DOI: 10.1039/C5OB00191A
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