Rhenium-catalyzed dehydrogenative olefination of C(sp3)–H bonds with hypervalent iodine(iii) reagents

Abstract

A dehydrogenative olefination of C(sp³)–H bonds is disclosed here, by merging rhenium catalysis with an alanine-derived hypervalent iodine(III) reagent. Thus, cyclic and acyclic ethers, toluene derivatives, cycloalkanes, and nitriles are all successfully alkenylated in a regio- and stereoselective manner.