Issue 46, 2015
From the journal:

Organic & Biomolecular Chemistry

Synthesis of indoles and polycyclic amides via ruthenium(ii)-catalyzed C–H activation and annulation†

Hui Lin,a   Shuai-Shuai Lia  and  Lin Dong*a  

* Corresponding authors

a Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China
E-mail: dongl@scu.edu.cn

Abstract

Ruthenium(II)-catalyzed oxidative coupling of NH protic amides with alkynes has been developed for the synthesis of a diversity of complex structures, such as N-acyl indole and tricyclic amide derivatives.

Graphical abstract: Synthesis of indoles and polycyclic amides via ruthenium(ii)-catalyzed C–H activation and annulation

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Article information

DOI
https://doi.org/10.1039/C5OB01788B
Article type
Paper
Submitted
26 Aug 2015
Accepted
15 Sep 2015
First published
17 Sep 2015

Org. Biomol. Chem., 2015,13, 11228-11234

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Synthesis of indoles and polycyclic amides via ruthenium(II)-catalyzed C–H activation and annulation

H. Lin, S. Li and L. Dong, Org. Biomol. Chem., 2015, 13, 11228 DOI: 10.1039/C5OB01788B

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