Issue 6, 2015

Lewis acid catalyzed Nazarov type cyclization for the synthesis of a substituted indane framework: total synthesis of (±)-mutisianthol

Abstract

A new synthetic route has been developed for the synthesis of a substituted indane derivative using Lewis acid catalyzed modified Nazarov type cyclization, which was further applied in the total synthesis of mutisianthol and epi-mutisianthol in a nine step longest linear sequence.

Graphical abstract: Lewis acid catalyzed Nazarov type cyclization for the synthesis of a substituted indane framework: total synthesis of (±)-mutisianthol

Supplementary files

Article information

Article type
Research Article
Submitted
03 Jan 2015
Accepted
07 Feb 2015
First published
11 Feb 2015

Org. Chem. Front., 2015,2, 645-648

Lewis acid catalyzed Nazarov type cyclization for the synthesis of a substituted indane framework: total synthesis of (±)-mutisianthol

D. H. Dethe, R. Boda and G. M. Murhade, Org. Chem. Front., 2015, 2, 645 DOI: 10.1039/C5QO00005J

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