Issue 6, 2015
From the journal:

Organic Chemistry Frontiers

Radical 5-exo cyclization of alkynoates with 2-oxoacetic acids for synthesis of 3-acylcoumarins†

Tong Liu,a   Qiuping Ding,*a   Qianshou Zongb  and  Guanyinsheng Qiu*b  

* Corresponding authors

a College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330013, China
E-mail: dqpjxnu@gmail.com

b College of Biological, Chemical Science and Engineering, Jiaxing University, 118 Jiahang Road, Jiaxing 314001, China
E-mail: 11110220028@fudan.edu.cn

Abstract

A silver-promoted decarboxylative annulation of alkynoates with 2-oxoacetic acids leading to the formation of 3-acyl-4-arylcoumarins is reported. The process involves radical decarboxylative acylation, 5-exo cyclization, and ester migration.

Graphical abstract: Radical 5-exo cyclization of alkynoates with 2-oxoacetic acids for synthesis of 3-acylcoumarins

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5QO00029G
Article type
Research Article
Submitted
26 Jan 2015
Accepted
30 Mar 2015
First published
31 Mar 2015

Org. Chem. Front., 2015,2, 670-673

Author version available

Download author version (PDF)

Permissions

Request permissions

Radical 5-exo cyclization of alkynoates with 2-oxoacetic acids for synthesis of 3-acylcoumarins

T. Liu, Q. Ding, Q. Zong and G. Qiu, Org. Chem. Front., 2015, 2, 670 DOI: 10.1039/C5QO00029G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements