Issue 12, 2015

2′-Cyanoethyl thioglycosides: effective nucleophiles for synthesis of (hetero)aryl thioglycosides under the catalysis of Cu

Abstract

2′-Cyanoethyl thioglycosides are designed and synthesized, which are demonstrated to function as powerful nucleophiles to a wide variety of organic iodides. The coupling reactions smoothly proceed under the catalysis of Cu to afford the corresponding (hetero)aryl thioglycosides in good to excellent yields.

Graphical abstract: 2′-Cyanoethyl thioglycosides: effective nucleophiles for synthesis of (hetero)aryl thioglycosides under the catalysis of Cu

Supplementary files

Article information

Article type
Research Article
Submitted
07 Sep 2015
Accepted
13 Oct 2015
First published
14 Oct 2015

Org. Chem. Front., 2015,2, 1604-1607

2′-Cyanoethyl thioglycosides: effective nucleophiles for synthesis of (hetero)aryl thioglycosides under the catalysis of Cu

X. Yuan, Y. Kou, L. Yu, Z. Zhang and W. Xue, Org. Chem. Front., 2015, 2, 1604 DOI: 10.1039/C5QO00276A

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