Enhancement of stereoselectivities in asymmetric synthesis using fluorinated solvents, auxiliaries, and catalysts

Abstract

Organofluorine compounds find diverse applications in the medicinal, agricultural, and material sciences. As a new application, certain organofluorine compounds have been used as ancillary materials in asymmetric synthesis. In this paper, we introduce the asymmetric transformations in which fluorinated solvents, additives, auxiliaries, and catalysts function to improve the stereoselectivities and/or the chemical yields.