Issue 4, 2015
From the journal:

RSC Advances

Enzyme-mediated preparation of hydrogels composed of poly(ethylene glycol) and gelatin as cell culture platforms†

Kousuke Moriyama,a   Rie Wakabayashi,a   Masahiro Gotoab  and  Noriho Kamiya*ab  

* Corresponding authors

a Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan
E-mail: nori_kamiya@mail.cstm.kyushu-u.ac.jp
Fax: +81 (0)92-802-2810
Tel: +81 (0)92-802-2806

b Center for Future Chemistry, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan

Abstract

A redox-responsive hydrogel composed of poly(ethylene glycol) and gelatin was prepared via an enzymatic oxidative reaction. Fibroblast cells adhered on the hydrogel showed proliferation and they could be recovered as a cell sheet by degradation of the scaffold under mild reductive conditions, thus providing a novel platform for cell culture.

Graphical abstract: Enzyme-mediated preparation of hydrogels composed of poly(ethylene glycol) and gelatin as cell culture platforms

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Article information

DOI
https://doi.org/10.1039/C4RA12334D
Article type
Communication
Submitted
14 Oct 2014
Accepted
21 Nov 2014
First published
10 Dec 2014

RSC Adv., 2015,5, 3070-3073

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Enzyme-mediated preparation of hydrogels composed of poly(ethylene glycol) and gelatin as cell culture platforms

K. Moriyama, R. Wakabayashi, M. Goto and N. Kamiya, RSC Adv., 2015, 5, 3070 DOI: 10.1039/C4RA12334D

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