BF3/nano-sawdust as a green, biodegradable and inexpensive catalyst for the synthesis of highly substituted dihydro-2-oxopyrroles

Abstract

BF₃/nano-sawdust was used as a readily available, inexpensive, biodegradable and environmentally benign heterogeneous solid acid catalyst for the one-pot cascade synthesis of highly functionalized dihydro-2-oxypyrroles. Four-component reactions (4CRs) of dialkylacetylenedicarboxylates, primary amines and aldehydes were used for the synthesis of these compounds under thermal conditions.