Issue 78, 2015
From the journal:

RSC Advances

Modulation of the stability of i-motif structures using an acyclic threoninol cytidine derivative†

Sonia Pérez-Rentero, ORCID logo a   Raimundo Gargallo,b   Carlos Gonzálezc  and  Ramon Eritja*a  

* Corresponding authors

a Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), CIBER-BBN, Jordi Girona 18-26, E-08034 Barcelona, Spain
E-mail: recgma@cid.csic.es

b Department of Analytical Chemistry, University of Barcelona, Martí i Franqués 1-11, E-08028 Barcelona, Spain

c Institute of Physical Chemistry “Rocasolano”, CSIC, Serrano 119, E-28006 Madrid, Spain

Abstract

The effect of aTNA (acyclic threoninol nucleic acids) units on the stability of intramolecular i-motifs was investigated by spectroscopic techniques. The replacement of selected positions of the C-core can modulate the stability at different pH ranges.

Graphical abstract: Modulation of the stability of i-motif structures using an acyclic threoninol cytidine derivative

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Article information

DOI
https://doi.org/10.1039/C5RA10096H
Article type
Communication
Submitted
28 May 2015
Accepted
17 Jul 2015
First published
20 Jul 2015
This article is Open Access
Creative Commons BY license

RSC Adv., 2015,5, 63278-63281

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Modulation of the stability of i-motif structures using an acyclic threoninol cytidine derivative

S. Pérez-Rentero, R. Gargallo, C. González and R. Eritja, RSC Adv., 2015, 5, 63278 DOI: 10.1039/C5RA10096H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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