Issue 84, 2015
From the journal:

RSC Advances

Synthesis, photophysical and anticancer study of D-ring extended estrone analogues†

Hardesh K. Maurya, ORCID logo a   Mohammad Hasanain,b   Ch. Pavan Kumar,c   Prema G. Vasudeva,d   Jayanta Sarkar,b   M. Chandrasekharamc  and  Atul Gupta*a  

* Corresponding authors

a Medicinal Chemistry Department, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow-226015, India
E-mail: atisky2001@yahoo.co.in, hardesh11@yahoo.co.in
Tel: +91 5222718556

b Division of Biochemistry, CSIR-Central Drug Research Institute, Sec-10, Jankipuram Extension, Lucknow, India

c I&PC Division, CSIR-Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad-500 607, India

d Metabolic & Structural Biology Department, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow-226015, India

Abstract

A concise route for the highly substituted ring extended estrone derivatives has been established. This protocol involves very simple, facile and one step ring transformation and cyclization process. The preliminary absorption, emission spectroscopic and biological studies of these compounds revealed the possible use of such prototypes in cancer chemotherapy as fluorescence probes.

Graphical abstract: Synthesis, photophysical and anticancer study of D-ring extended estrone analogues

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5RA11112A
Article type
Communication
Submitted
11 Jun 2015
Accepted
03 Aug 2015
First published
04 Aug 2015

RSC Adv., 2015,5, 68843-68851

Permissions

Request permissions

Synthesis, photophysical and anticancer study of D-ring extended estrone analogues

H. K. Maurya, M. Hasanain, Ch. P. Kumar, P. G. Vasudeva, J. Sarkar, M. Chandrasekharam and A. Gupta, RSC Adv., 2015, 5, 68843 DOI: 10.1039/C5RA11112A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements