Issue 80, 2015

A concise route to functionalized benzofurans directly from gem-dibromoalkenes and phenols

Abstract

A tandem strategy for the construction of benzofuran motifs has been developed directly from gem-dibromoalkenes and phenols under palladium-catalyzed conditions. This flexible and novel methodology provides direct access to 2-aryl and 2-styryl benzofurans in good to high yields. This strategy is also valuable in the synthesis of benzodifurans.

Graphical abstract: A concise route to functionalized benzofurans directly from gem-dibromoalkenes and phenols

Supplementary files

Article information

Article type
Paper
Submitted
06 Jul 2015
Accepted
24 Jul 2015
First published
31 Jul 2015
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2015,5, 65462-65470

A concise route to functionalized benzofurans directly from gem-dibromoalkenes and phenols

M. L. N. Rao and P. Dasgupta, RSC Adv., 2015, 5, 65462 DOI: 10.1039/C5RA13213D

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