A common protocol for the synthesis of amides, esters and α-ketoesters via cross dehydrogenative coupling of aldehydes and amines/alcohols has been developed. The method is applicable to a wide variety of alcohols and amines as well as aliphatic and aromatic aldehydes. Also, the use of acetaldehyde for acetylation and ethyl glyoxalate to access 2-oxo-amino esters is presented for the first time.
R. Deshidi, M. A. Rizvi and B. A. Shah, RSC Adv., 2015, 5, 90521 DOI: 10.1039/C5RA17425B
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