Issue 17, 2015
From the journal:

Journal of Materials Chemistry B

Unusual self-assembly of a hydrophilic β-cyclodextrin inclusion complex into vesicles capable of drug encapsulation and release†

Nagaraj Nayakab  and  Karical R. Gopidas*ab  

* Corresponding authors

a Photosciences and Photonics Section, Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Council of Scientific and Industrial Research (CSIR), Trivandrum 695019, India
E-mail: gopidaskr@niist.res.in

b Academy of Scientific and Innovative Research (AcSIR), New Delhi 110001, India

Abstract

Formation of a hydrophilic β-cyclodextrin bis-inclusion complex and its self-assembly into supramolecular vesicles are described. The vesicles can be loaded with the anti-cancer drug doxorubicin and the loaded drug can be released upon addition of a competitive inclusion binder such as adamantane carboxylate.

Graphical abstract: Unusual self-assembly of a hydrophilic β-cyclodextrin inclusion complex into vesicles capable of drug encapsulation and release

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Article information

DOI
https://doi.org/10.1039/C4TB02114B
Article type
Communication
Submitted
22 Dec 2014
Accepted
28 Mar 2015
First published
31 Mar 2015

J. Mater. Chem. B, 2015,3, 3425-3428

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Unusual self-assembly of a hydrophilic β-cyclodextrin inclusion complex into vesicles capable of drug encapsulation and release

N. Nayak and K. R. Gopidas, J. Mater. Chem. B, 2015, 3, 3425 DOI: 10.1039/C4TB02114B

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