G-quadruplex-based logic gates for HgII and AgI ions employing a luminescent iridium(iii) complex and extension of metal-mediated base pairs by polymerase

Abstract

We report herein the synthesis of a series of cyclometallated iridium(III) complexes as luminescent G-quadruplex-selective probes, which were used to construct AND, OR and INHIBIT logic gates for the detection of Hg^II and Ag^I ions. To our knowledge, this is the first time that the C–Ag^I–T mismatched base pair has been used for the construction of luminescent assays or logic gates.