Issue 18, 2016

Enzymatic conversion of magnetic nanoparticles to a non-magnetic precipitate: a new approach to magnetic sensing

Abstract

Magnetic sensing utilizes the detection of biomolecule-conjugated magnetic nanoparticles (MNPs). Our new strategy offers a novel approach to magnetic sensing where in situ conversion produces a “loss of signal” in the sensing device. This report demonstrates the enzymatic conversion of Fe3O4 MNPs to a non-magnetic precipitate via reduction by L-ascorbic acid generated by the action of alkaline phosphatase.

Graphical abstract: Enzymatic conversion of magnetic nanoparticles to a non-magnetic precipitate: a new approach to magnetic sensing

Article information

Article type
Communication
Submitted
25 Mar 2016
Accepted
24 Jul 2016
First published
25 Jul 2016

Analyst, 2016,141, 5246-5251

Enzymatic conversion of magnetic nanoparticles to a non-magnetic precipitate: a new approach to magnetic sensing

A. G. Kolhatkar, A. C. Jamison, I. Nekrashevich, K. Kourentzi, D. Litvinov, A. Brazdeikis, R. C. Willson and T. Randall Lee, Analyst, 2016, 141, 5246 DOI: 10.1039/C6AN00709K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements