A nanoplasmonic ruler method is presented in order to measure the deformation of adsorbed, nm-scale lipid vesicles on solid supports. It is demonstrated that single adsorbed vesicles undergo greater deformation on silicon oxide over titanium oxide, offering direct experimental evidence to support membrane tension-based theoretical models of supported lipid bilayer formation.
J. A. Jackman, B. Špačková, E. Linardy, M. C. Kim, B. K. Yoon, J. Homola and N. Cho, Chem. Commun., 2016, 52, 76 DOI: 10.1039/C5CC06861D
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