Issue 13, 2016
From the journal:

Chemical Communications

DNA aptamer release from the DNA–SWNT hybrid by protein recognition†

Chang-Hyuk Yoo,ab   Seungwon Jung,abc   Jaehyun Bae,d   Gunn Kim,e   Jisoon Ihmd  and  Junghoon Lee*ab  

* Corresponding authors

a School of Mechanical and Aerospace Engineering, Seoul National University, Seoul 151-742, Republic of Korea
E-mail: jleenano@snu.ac.kr

b Inter-Semiconductor Research Center, Seoul National University, Seoul 151-742, Republic of Korea

c Center for Biomicrosystems, Korea Institute of Science and Technology, Seoul 136-791, Republic of Korea

d FPRD and Department of Physics and Astronomy, Seoul National University, Seoul 151-742, Republic of Korea

e Department of Physics, Sejong University, Seoul 143-747, Republic of Korea

Abstract

Here we show the formation of the complex between a DNA aptamer and a single-walled carbon nanotube (SWNT) and its reaction with its target protein. The aptamer, which is specifically bound with thrombin, the target protein in this study, easily wraps and disperses the SWNT by noncovalent π–π stacking.

Graphical abstract: DNA aptamer release from the DNA–SWNT hybrid by protein recognition

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Article information

DOI
https://doi.org/10.1039/C5CC07726E
Article type
Communication
Submitted
15 Sep 2015
Accepted
04 Jan 2016
First published
04 Jan 2016

Chem. Commun., 2016,52, 2784-2787

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DNA aptamer release from the DNA–SWNT hybrid by protein recognition

C. Yoo, S. Jung, J. Bae, G. Kim, J. Ihm and J. Lee, Chem. Commun., 2016, 52, 2784 DOI: 10.1039/C5CC07726E

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