Issue 13, 2016
From the journal:

Chemical Communications

Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy†

Guorui Jin,‡a   Guangxue Feng,b   Wei Qin,c   Ben Zhong Tang,cd   Bin Liu*ab  and  Kai Li§*a  

* Corresponding authors

a Institute of Materials Research and Engineering, A*STAR, 2 Fusionopolis Way, Innovis, #08-03, Singapore
E-mail: kai_li_cn@hotmail.com

b Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore
E-mail: cheliub@nus.edu.sg

c Department of Chemistry, Institute for Advanced Study, Institute of Molecular Functional Materials, Division of Biomedical Engineering, Division of Life Science, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China

d Guangdong Innovative Research Team, SCUT-HKUST Joint Research Laboratory, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, China

Abstract

We report the design of AIE fluorogen (AIEgen)-based multifunctional organic nanoparticles with surface siRNA decoration for targeted photodynamic therapy and RNA interference therapy.

Graphical abstract: Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy

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Article information

DOI
https://doi.org/10.1039/C5CC07818K
Article type
Communication
Submitted
18 Sep 2015
Accepted
04 Jan 2016
First published
04 Jan 2016

Chem. Commun., 2016,52, 2752-2755

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Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy

G. Jin, G. Feng, W. Qin, B. Z. Tang, B. Liu and K. Li, Chem. Commun., 2016, 52, 2752 DOI: 10.1039/C5CC07818K

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