We describe the first ring-opening of furfuryl alcohols with boronic acids to afford functionalized γ-ketoaldehydes. The transformation builds a new C–C bond at the original C-4 of the starting furan, and tolerates ring-substitution at C-3 and C-4 positions. The reaction takes place under metal-free conditions by promotion with tartaric acid.
S. Roscales and A. G. Csákÿ, Chem. Commun., 2016, 52, 3018 DOI: 10.1039/C5CC08809G
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