Issue 33, 2016
From the journal:

Chemical Communications

Thermal-activated nanocarriers for the manipulation of cellular uptake and photothermal therapy on command†

Jingjing Zhao,‡a   Penghui Zhang,‡a   Zhimei He,a   Qian-Hao Min,a   E. S. Abdel-Halimb  and  Jun-Jie Zhu*a  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China
E-mail: jjzhu@nju.edu.cn
Fax: +86-25-8968-7204
Tel: +86-25-8968-7204

b Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia

Abstract

Smart nanocarriers with switchable surfaces consisting of thermo-sensitive polymers and aptamers have been developed, through which the cellular uptake and photothermal therapy in five different cells could be spatial-temporally controlled on command, which is beneficial in maximizing therapy efficacy and minimizing side effects.

Graphical abstract: Thermal-activated nanocarriers for the manipulation of cellular uptake and photothermal therapy on command

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Article information

DOI
https://doi.org/10.1039/C6CC01162D
Article type
Communication
Submitted
04 Feb 2016
Accepted
18 Mar 2016
First published
18 Mar 2016

Chem. Commun., 2016,52, 5722-5725

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Thermal-activated nanocarriers for the manipulation of cellular uptake and photothermal therapy on command

J. Zhao, P. Zhang, Z. He, Q. Min, E. S. Abdel-Halim and J. Zhu, Chem. Commun., 2016, 52, 5722 DOI: 10.1039/C6CC01162D

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