Issue 59, 2016
From the journal:

Chemical Communications

DNA-catalyzed glycosylation using aryl glycoside donors†

Anthony R. Hesser,‡a   Benjamin M. Brandsen,‡a   Shannon M. Walsh,a   Puzhou Wang ORCID logo a  and  Scott K. Silverman ORCID logo *a  

* Corresponding authors

a Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
E-mail: scott@scs.illinois.edu

Abstract

We report the identification by in vitro selection of Zn2+/Mn2+-dependent deoxyribozymes that glycosylate the 3′-OH of a DNA oligonucleotide. Both β and α anomers of aryl glycosides can be used as the glycosyl donors. Individual deoxyribozymes are each specific for a particular donor anomer.

Graphical abstract: DNA-catalyzed glycosylation using aryl glycoside donors

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DOI
https://doi.org/10.1039/C6CC04329A
Article type
Communication
Submitted
23 May 2016
Accepted
18 Jun 2016
First published
22 Jun 2016
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 9259-9262

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DNA-catalyzed glycosylation using aryl glycoside donors

A. R. Hesser, B. M. Brandsen, S. M. Walsh, P. Wang and S. K. Silverman, Chem. Commun., 2016, 52, 9259 DOI: 10.1039/C6CC04329A

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