Issue 82, 2016

A capillary-based multiplexed isothermal nucleic acid-based test for sexually transmitted diseases in patients

Abstract

We demonstrate a multiplexed loop mediated isothermal amplification (LAMP) assay for infectious disease diagnostics, where the analytical process flow of target pathogens genomic DNA is performed manually by moving magnetic beads through a series of plugs in a capillary. Heat is provided by a water bath and the results are read by the naked eye, enabling applications in low resource settings.

Graphical abstract: A capillary-based multiplexed isothermal nucleic acid-based test for sexually transmitted diseases in patients

Supplementary files

Article information

Article type
Communication
Submitted
10 Jul 2016
Accepted
08 Sep 2016
First published
08 Sep 2016
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 12187-12190

A capillary-based multiplexed isothermal nucleic acid-based test for sexually transmitted diseases in patients

G. Xu, H. Zhao, J. M. Cooper and J. Reboud, Chem. Commun., 2016, 52, 12187 DOI: 10.1039/C6CC05679B

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