Issue 87, 2016
From the journal:

Chemical Communications

Electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence signal amplification strategy on a microchip platform for highly sensitive detection of microRNA†

Jian Li,a   Jingjin Zhao,*a   Shuting Li,a   Liangliang Zhang,a   Yong Huang,a   Shulin Zhao*a  and  Yi-Ming Liub  

* Corresponding authors

a State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China
E-mail: zhaoshulin001@163.com, jzhao12@163.com
Fax: +86-773-583-2294
Tel: +86-0773-2120226

b Department of Chemistry and Biochemistry, Jackson State University, 1400 Lynch St, Jackson, MS 39217, USA

Abstract

We have developed an electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence (CL) signal amplification strategy on a microchip platform for the detection of trace microRNA. This strategy exhibits high sensitivity and specificity for detection of target molecules.

Graphical abstract: Electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence signal amplification strategy on a microchip platform for highly sensitive detection of microRNA

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Article information

DOI
https://doi.org/10.1039/C6CC06327F
Article type
Communication
Submitted
31 Jul 2016
Accepted
30 Aug 2016
First published
31 Aug 2016

Chem. Commun., 2016,52, 12806-12809

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Electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence signal amplification strategy on a microchip platform for highly sensitive detection of microRNA

J. Li, J. Zhao, S. Li, L. Zhang, Y. Huang, S. Zhao and Y. Liu, Chem. Commun., 2016, 52, 12806 DOI: 10.1039/C6CC06327F

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